Meridia is a weight loss medication, affecting specific areas of the brain responsible for the feeling of satiety. Adipex is referred to the same category of drugs, although its scope of action aims at suppressing appetite. The drug Meridia is manufactured by the German company Knoll AG, while Adipex is produced by Gate Pharmaceuticals, a division of Teva in the US. Both drugs have different active substances: in Meridia it is sibutramine, curbing an overwhelming feeling of hunger and forming a feeling of satiety, providing a reduction in consumed foods by up to 30% even during the first days of treatment.
Adipex is based on phentermine, the active ingredient allowing you to cope with your hunger and burn fat faster. However, while Adipex is still available by prescription in the US, Meridia was discontinued by FDA in 2010.
In the European tests of the medication involving 20,000+ participants, Meridia has demonstrated a weight reduction by at least 5%, although the results were quite uneven. In addition to the main action, the use of the drug leads to a normalization of the level of triglycerides, lipoproteins, glucose, C-peptide, cholesterol, glycosylated hemoglobin, and uric acid. This is due to the fact that the process of power adjustment leads to better digestion and contraindications prevent the deposition of excess fat in the body.
The course of treatment less than 3 months is not effective. In severe cases, the drug is assigned for ongoing reception. The initial dose is one capsule (10 mg) daily, and the average duration ranges from 4 to 6 months. The drug costs around $135 per 30 days course, which is 2.2 times more expensive in comparison with Adipex (priced at $50 – $60 range).
Adipex is designed for short term use, the average treatment course doesn’t exceed 4 – 5 weeks (and the maximum treatment duration must not exceed 12 weeks). According to clinical trials it provides a 3 – 4% weight loss result. However, one of the main downsides of the drug against the background of Meridia is obligatory lifestyle changes (following a healthy diet plan, exercising regularly, etc.); otherwise the treatment is considered to be ineffective.